@import url('https://fonts.googleapis.com/css2?family=Crimson+Text:ital,wght@0,400;0,600;0,700;1,400;1,600;1,700&family=Lora:ital,wght@0,400..700;1,400..700&family=Playfair+Display:ital,wght@0,400..900;1,400..900&family=Source+Code+Pro:ital,wght@0,200..900;1,200..900&display=swap');

* {
    margin: 0;
    padding: 0;
    box-sizing: border-box;
    font-family: Lato, sans-serif;
    /* font-family: MS PMincho; */
    /* font-family: Arial, sans-serif; */
}

html,
body {
    font-size: 18px;
    line-height: 1.5;
    color: rgba(0, 0, 0, 1);
}

.align-center {
    text-align: center;
    width: 100%;
    display: block;
}

.pl-12 {
    padding-left: 12px;
}

.p-8 {
    padding: 8px 0;
}

.op-5 {
    opacity: 0.5;
}

.mt-30 {
    margin-top: 30px !important;
}

.d-none {
    display: none;
}

.col-w-900 {
    max-width: 900px;
    margin: 0 auto;
}

.col-w-365 {
    max-width: 365px;
    margin: 0 auto;
}

.font-arial>*,
.font-arial {
    font-family: 'Arial';
}

.text-m-w-843 {
    max-width: 843px;
    margin-left: auto;
    margin-right: auto;
}

.mx-auto {
    margin: 0 auto;
}

.img-w-83 {
    width: 83.33%;
}

.img-w-66 {
    width: 66.66%;
}

.img-w-50 {
    width: 50%;
}

.gap-top-0 {
    margin-top: -40px !important;
}

.flex {
    display: flex;
}

.justify-center {
    justify-content: center;
}

a.link-black,
ol a {
    position: relative;
}

a.link-black::before,
ol a::before {
    content: "";
    position: absolute;
    bottom: -5px;
    left: 0;
    width: 100%;
    height: 2px;
    background: linear-gradient(to right, rgb(0 105 133), rgb(0 95 133), rgb(0 85 133));
    z-index: 1;
    transform: scaleX(0);
    transform-origin: left;
    transition: transform 0.5s ease-in-out;
}

a.link-black:hover,
ol a:hover {
    opacity: 1;
}

a.link-black:hover::before,
ol a:hover::before {
    transform: scaleX(1);
}

@media only screen and (min-width: 769px) {

    .mr-md-0 {
        margin-right: 0px !important;
    }

    .ml-md-0 {
        margin-left: 0px !important;
    }

    .space-top-40 {
        margin-top: 40px;
    }
}

@media only screen and (max-width: 768px) {

    .img-w-83 {
        width: 100%;
    }

    .img-w-66 {
        width: 100%;
    }

    .img-w-50 {
        width: 100%;
    }

    .gap-top-0 {
        margin-top: -25px !important;
    }
}

@media only screen and (max-width: 425px) {

    .gap-top-0 {
        margin-top: -20px !important;
    }
}

/* text */
a.h3-link {
    color: rgba(0, 101, 128, 1);
    margin: 30px 0;
    font-size: 48px;
    font-weight: 400;
    text-decoration: underline;
    height: 120px;
}

a.external-link {
    padding: 5px 12px;
    font-family: Lato, sans-serif;
    font-size: 20px;
    font-weight: 500;
    color: rgb(222 185 39);
    text-decoration: none;
    background-color: #000000;
    border-radius: 6px;
    text-align: center;
    cursor: pointer;
    text-decoration: none;
    position: relative;
}

/* a.external-link::after {
    content: '';
    width: 1em;
    height: 1em;
    font-size: 15px;
    background-image: url(../icon/arrow-up-right-from-square-solid.svg);
    background-size: cover;
    top: 50%;
    right: 15px;
    transform: translateY(-50%);
    position: absolute;
    filter: brightness(0) saturate(100%) invert(33%) sepia(90%) saturate(430%) hue-rotate(155deg) brightness(91%) contrast(88%);
} */

a.button-link {
    border: 1px solid rgba(30, 108, 147, 1);
    color: rgba(30, 108, 147, 1);
    font-family: Lato, sans-serif;
    font-size: 15px;
    display: block;
    border-radius: 4px;
    text-align: center;
    padding: 8px;
    margin-bottom: 15px;
    cursor: pointer;
    text-decoration: none;
}

a.button-link:hover {
    background-color: rgba(30, 108, 147, 0.1000000015);
}

strong {
    font-weight: 700;
}

p {

    margin-bottom: 15px;
    /* line-height: 1.8; */
}

p.small-text {
    font-size: 16px;
}

p.small-label {
    font-size: 14px;
}

span.small-span {
    font-size: 12px;
}

h2.description {
    color: rgb(34, 110, 147);
    font-family: Lato, sans-serif;
    font-size: 25px;
    font-weight: 400;
    line-height: 1.3;
    margin-bottom: 10px;
}

h2.big-label {
    font-family: Lato, sans-serif;
    font-size: 45px;
    font-weight: 300;
    line-height: 1.3;
    color: #FFFFFF;
}

h1,
h2,
h3 {
    margin-bottom: 20px;
    line-height: 1.8;
}

h4,
h5 {
    margin-bottom: 10px;
    line-height: 1.8;
}

h2 {
    font-size: 40px;
    font-weight: 300;
}

.big-text {
    font-size: 18px !important;
}

.text-blue {
    color: rgb(34, 110, 147) !important;
}

.text-black {
    color: #333333 !important;
}

.text-white {
    color: #ffffff !important;
}

h3 {
    font-size: 24px;
    color: #000000;
    font-weight: 400;
}

h4 {
    font-size: 20px;
    color: rgb(51, 51, 51);
    font-weight: 700;
}

ol,
ul {
    text-align: left;
    /* font-size: 16px; */
    padding-top: 0px;
    padding-left: 20px;
}

ol li,
ol a {
    color: rgba(0, 101, 128, 1);
    /* color: #000000; */
    text-decoration: none;
}

ol li,
ul li {
    margin-bottom: 15px;
}

@media only screen and (max-width: 1920px) {
    section.two-col p {
        font-size: 16px;
        line-height: 1.6;
    }

    h2 {
        font-size: 36px;
    }
}

@media only screen and (max-width: 1500px) {}

@media only screen and (max-width: 1080px) {
    a.h3-link {
        font-size: 36px;
        height: auto;
    }

    h2 {
        font-size: 48px;
    }

    h2.big-label {
        font-size: 54px;
    }
}

@media only screen and (max-width: 768px) {
    p {
        font-size: 16px;
    }

    h2.description {
        font-size: 22px;
    }

    h1,
    h2,
    h3 {
        margin-bottom: 15px;
        line-height: 1.5;
    }

    h4,
    h5 {
        margin-bottom: 10px;
        line-height: 1.5;
    }

    h2 {
        font-size: 28px;
    }

    h4 {
        font-size: 18.5px;
    }

    h2.big-label {
        font-size: 38px;
    }
}

@media only screen and (max-width: 425px) {
    h2 {
        font-size: 26px;
    }

    h2.description {
        font-size: 20px;
    }

    h2.big-label {
        font-size: 32px;
    }
}


.logo-bar {
    display: flex;
    gap: 10px;
    align-items: stretch;
    position: relative;
    margin-bottom: 25px;
}

.logo-bar .logo {
    margin-left: 20px;
    display: flex;
}

.logo-bar .logo img {
    width: 90px;
    height: auto;
    aspect-ratio: 1 / 1;
    object-fit: cover;
    margin: 0;
}

.logo-bar .text {
    border-left: 3px solid #5a79a6;
    padding-left: 10px;
    display: flex;
    align-items: center;
    font-size: 26px;
    color: #5b7ba7;
    font-weight: 600;
}

.logo-bar .bottom-line {
    background: rgb(91, 123, 167);
    width: 100%;
    position: absolute;
    bottom: -25px;
    height: 6px;
    background: linear-gradient(90deg, rgba(91, 123, 167, 1) 35%, rgba(255, 255, 255, 1) 100%);
}

@media only screen and (max-width: 768px) {
    .logo-bar .logo img {
        max-width: 60px;
    }

    .logo-bar .text {
        font-size: 20px;
    }
}

/* main */

html {
    scrollbar-width: thin;
    overflow-x: hidden;
}

section.bg-gray .column,
section.bg-blue .column {
    position: relative;
    z-index: 5;
}

section.bg-blue {
    position: relative;
}

section.bg-blue p {
    color: #FFFFFF;
}

section.bg-blue::after {
    content: '';
    position: absolute;
    top: 0;
    left: 50%;
    height: 100%;
    width: calc(100vw - 10px);
    transform: translateX(-50%);
    background-color: #1e6c93;
    z-index: 1;
}

section.bg-gray {
    position: relative;
}

section.bg-gray p {
    color: rgb(33, 33, 33);
}

a.link-black {
    /* color: rgb(0, 0, 0); */
    color: rgb(0, 101, 128);
    text-decoration: none;
    font-weight: 700;
}

a.link-blue {
    color: rgb(0, 101, 128);
}

section.bg-gray::after {
    content: '';
    position: absolute;
    top: 0;
    left: 50%;
    height: 100%;
    width: calc(100vw - 10px);
    transform: translateX(-50%);
    background-color: #f2f2f2;
    z-index: -1;
}

img {
    width: 100%;
    margin-bottom: 15px;
}

button:hover,
a:hover {
    opacity: 0.8;
}

.menu {
    position: fixed;
    padding-left: 16px;
    left: 0;
    top: 0;
    z-index: 99;
    display: flex;
    flex-direction: column;
}

.menu ul {
    list-style: none;
    display: flex;
    gap: 15px;
    padding: 16px 0;
}

.menu-item {
    padding: 5px 12px;
    font-family: Lato, sans-serif;
    font-size: 20px;
    font-weight: 500;
    color: rgb(222 185 39);
    text-decoration: none;
    background-color: #000000;
    border-radius: 6px;
}

.menu-button {
    width: 45px;
    height: 40px;
    background: unset;
    border: unset;
    margin: 5px 0 0px;
    display: none;
    background-color: #FFFFFF;
    border-radius: 8px;
    padding: 5px;
}

body {
    background-color: #FFFFFF;
    color: #333;
}

header {
    text-align: center;
    position: relative;
    color: #333;
    min-height: 150px;
}

.home {
    padding-top: 60px;
}

header>img.big-banner {
    min-height: 520px;
}
header:not(.home)>img.big-banner {
    aspect-ratio: 1920 / 520;
}
header>img {
    width: 100%;
    /* min-height: 520px; */
    min-height: 360px;
    object-fit: cover;
    margin: 0;
    vertical-align: middle;
}

header:not(.home)>img {
    /* aspect-ratio: 1920 / 520; */
    aspect-ratio: 1920 / 360;
}

header img.thumbnail {
    width: 100%;
    aspect-ratio: unset;
    min-height: unset;
    max-width: 760px;
}

.page-home header img.thumbnail {
    max-width: 1000px;
    margin-bottom: 80px;
}

.page-home header .content {
    top: 55%;
}

.page-home section.two-col{
    max-width: 1080px;
}
.page-home a.h3-link{
    font-size: 43px;
}
.page-home ol a{
    font-size: 20px;
}



header .content {
    position: absolute;
    top: 50%;
    left: 50%;
    z-index: 1;
    transform: translate(-50%, -50%);
    width: 100%;
    padding: 0 15px;
}

/* header.home .content {
    top: 65%;
} */

header .content h1 {
    font-size: 64px;
    font-family: Lato, sans-serif;
    /* font-family: "Lora", serif; */
    font-optical-sizing: auto;
    /* font-weight: 300; */
    font-weight: 700 !important;
    margin-bottom: 10px;
    min-width: 75%;
    line-height: 1.4;
}

header .content h1.small {
    font-size: 34px;
    font-weight: 300;
    line-height: 1.2;
}


main {
    /* background-color: #FFFFFF; */
    padding: 0 20px;
    display: flex;
    flex-direction: column;
    gap: 40px;
}

section {
    display: flex;
    flex-direction: column;
}

section.two-col {
    display: flex;
    flex-direction: row;
}

section,
section.two-col {
    width: 100%;
    margin: 0 auto;
    max-width: 1200px;
    gap: 30px;
    padding: 20px 30px;
    justify-content: space-around;
}

.column {
    flex: 1;
}

.column.col-10 {
    max-width: 10%;
}

.column.col-90 {
    max-width: 90%;
}

.column.col-15 {
    max-width: 15%;
}

.column.col-85 {
    max-width: 85%;
}

.column.col-25 {
    max-width: 25%;
}

.column.col-75 {
    max-width: 75%;
}

.column.col-66 {
    max-width: 66.66%;
}

.column.col-34 {
    max-width: 33.34%;
}

section.two-col img {
    width: 100%;
    height: auto;
    margin-bottom: 20px;
}


footer {
    text-align: center;
    padding: 20px;
    margin-top: 100px;
    min-height: 100px;
    font-size: 14px;
    display: flex;
    color: #888;
    align-items: center;
    justify-content: center;
}

@media only screen and (max-width: 1500px) {
    header .content h1 {
        font-size: 54px;
    }

    .page-home header img.thumbnail {
        max-width: 800px;
        margin-bottom: 60px;
    }
}

@media only screen and (max-width: 1080px) {

    /* header.home .content {
        top: 70%;
    } */
    .page-home header img.thumbnail {
        max-width: 600px;
        margin-bottom: 40px;
    }

    header .content h1 {
        font-size: 48px;
    }

    header>img {
        min-height: 460px;
    }

    .menu ul {
        flex-direction: column;
        background-color: #FFFFFF;
        width: 100%;
        box-shadow: 1px 1px 15px #333333;
        position: fixed;
        z-index: -1;
        left: 0;
        top: 0;
        transform: translateY(-120%);
        padding-top: 60px;
        padding-left: 10px;
    }

    .menu ul.show {
        transform: translateY(0%);
    }

    .menu-button {
        display: flex;
        align-items: center;
        justify-content: center;
        cursor: pointer;
    }
}

@media only screen and (max-width: 768px) {
    main {
        padding: 0 10px;
        gap: 25px;
    }

    .page-home header img.thumbnail {
        max-width: 560px;
        margin-bottom: 30px;
    }

    /* .column.col-90,
    .column.col-10, */

    .column.col-85,
    .column.col-15,
    .column.col-66,
    .column.col-34,
    .column.col-75,
    .column.col-25 {
        max-width: 100%;
    }

    footer {
        margin-top: 60px;
    }

    /* header.home .content {
        top: 70%;
    } */

    header .content h1 {
        font-size: 36px;
    }

    header .content h1.small {
        font-size: 30px;
    }

    header>img {
        min-height: 400px;
    }

    section,
    section.two-col {
        padding: 10px 15px;
        flex-direction: column;
        max-width: 544px;
    }

    section img {
        margin-bottom: 10px;
    }

    a.h3-link,
    ol li,
    ul li,
    p {
        margin-bottom: 8px;
    }

    .p-8 {
        padding: 0;
    }

    .sm-m-w-216 {
        max-width: 216px;
    }
}

@media only screen and (max-width: 425px) {
    main {
        gap: 20px;
    }

    header .content h1 {
        font-size: 32px;
    }
}

/* page style */

/* .page-exosome .menu-item {
    color: rgb(255, 255, 255);
} */

.page-telomere h2,
.page-telomere h3,
.page-telomere h4,
.page-telomere p,
.page-exosome h1,
.page-exosome h2,
.page-exosome h3,
.page-exosome h4,
.page-exosome p {
    font-family: 'Arial';
}

.page-anti-aging-for-beauty p {
    font-family: 'Arial';
    line-height: 2;
    font-size: 15px;
    color: #666666;
}

.page-telomere section.two-col p,
.page-telomere p,
.page-exosome p {
    color: #666666;
    font-weight: 400;
    line-height: 2;
}

.page-telomere p {
    font-size: 16px;
}

.page-telomere-length-test section.two-col img {
    margin-bottom: 10px;
}

.page-telomere-length-test section.two-col p,
.page-telomere-length-test p {
    font-size: 15px;
}

.page-lengthen-telomere main {
    gap: 20px;
}

.page-lengthen-telomere header h1.small {
    margin-bottom: 20px;
}

.page-lengthen-telomere header .background-image::before {
    background-color: rgba(33, 33, 33, 1);
    opacity: 0.4;
    display: block;
    bottom: 0;
    content: "";
    left: 0;
    pointer-events: none;
    position: absolute;
    right: 0;
    top: 0;
}

.page-lengthen-telomere header .background-image {
    min-height: 400px;
    background-color: rgba(34, 110, 147, 1);
    background-image: url(../image/TAM_banner.png);
    background-repeat: no-repeat;
    background-size: cover;
    position: relative;
}

.page-lengthen-telomere header .header-content {
    gap: 100px;
    display: flex;
    justify-content: center;
    align-items: center;
}

.page-lengthen-telomere header .content h1{
    font-size: 54px;
}

.page-lengthen-telomere section.two-col p,
.page-lengthen-telomere p {
    font-size: 15px;
    line-height: 1.677;
}

@media only screen and (max-width: 1500px) {
    .page-lengthen-telomere header .content h1{
        font-size: 46px;
    }
}

@media only screen and (max-width: 1080px) {
    .page-lengthen-telomere header .header-content {
        gap: 40px;
    }

    .page-lengthen-telomere header .content h1{
        font-size: 42px;
    }
}

@media only screen and (max-width: 768px) {
    .page-lengthen-telomere header .background-image {
        min-height: 520px;
    }

    .page-lengthen-telomere header .content h1{
        font-size: 36px;
    }

    .page-lengthen-telomere header .header-content {
        flex-direction: column;
        gap: 20px;
    }

    .page-lengthen-telomere header img.thumbnail {
        max-width: 150px;
    }
}

.page-anti-aging-for-beauty header .content h1 {
    font-size: 48px;
    font-weight: 300;
}

@media only screen and (max-width: 1080px) {
    .page-anti-aging-for-beauty header .content h1 {
        font-size: 42px;
    }
}

@media only screen and (max-width: 768px) {
    .page-anti-aging-for-beauty header .content h1 {
        font-size: 36px;
    }
}

@media only screen and (max-width: 425px) {
    .page-anti-aging-for-beauty header .content h1 {
        font-size: 28px;
    }
}

.page-injection-system main {
    gap: 0px;
}

.page-injection-system h2 {
    font-size: 26px;
}

@media only screen and (max-width: 768px) {
    .page-injection-system h2 {
        font-size: 18px;
    }
}

h3 {
    color: rgba(0, 101, 128, 1);
}

.bg-light-blue {
    background-color: #E8F2FC;
}

.number-blue {
    padding: 0;
    color: #C6E1FF;
    font-size: 300px;
    font-family: Impact, Haettenschweiler, 'Arial Narrow Bold', sans-serif;
    line-height: 1;
}

.number-blue-1 {
    margin-left: -30px;
}

.number-blue-2 {
    z-index: 0;
    margin-left: -35px;
    margin-right: -35px;
}

.z-index-2 {
    z-index: 2;
}

.number-blue-3 {
    z-index: 0;
    margin-right: -150px;
}

@media screen and (max-width: 1024px) {
    .number-blue {
        font-size: 200px;
    }
}

@media screen and (max-width: 768px) {
    .number-blue {
        font-size: 100px;
    }

    .number-blue-1 {
        margin-left: 10px;
        margin-bottom: -50px;
    }

    .row:has(.number-blue-2) {
        flex-direction: column-reverse;
    }

    .number-blue-2 {
        margin-left: 10px;
        margin-right: 0;
        margin-bottom: -50px;
    }

    .number-blue-3 {
        margin-right: 0;
        margin-bottom: -50px;
    }
}

.bg-grey {
    background-color: #eee;
}

.box-brown {
    border: 3px solid rgb(138, 111, 75);
    max-width: 800px;
    margin: auto;
    width: 100%;
}

.box-brown img {
    margin-bottom: 0;
}

.polygon-down-container {
    background-color: #000;
    padding: 2px;
    clip-path: polygon(0 0, 100% 0, 100% 50%, 50% 100%, 50% 100%, 0% 50%);
    max-width: 400px;
    margin: 0 auto;
}

.polygon-down {
    text-align: center;
    color: #fff;
    font-weight: bold;
    background-color: grey;
    clip-path: polygon(0 0, 100% 0, 100% 50%, 50% 100%, 50% 100%, 0% 50%);
    padding: 20px 10px 30px 10px;
}

.box-black {
    border: 2px solid #000;
}

.rectangle-green {
    background-color: #04a17f;
    max-width: 400px;
    margin: 0 auto;
    color: #fff;
    font-weight: bold;
    position: relative;
}

.rectangle-green.arrow-down::before {
    position: absolute;
    content: '';
    bottom: -10px;
    left: 50%;
    transform: translateX(-50%) rotate(45deg);
    background-color: #04a17f;
    width: 20px;
    height: 20px;

}

.triangle-down {
    width: fit-content;
    margin: 0 auto;
    background-color: #000;
    padding: 5px 100px;
    color: #fff;
    clip-path: polygon(50% 100%, 0 0, 100% 0);
}

.pill {
    background-color: #000;
    color: #fff;
    padding: 5px 10px;
    border-radius: 10px;
    width: fit-content;
    font-weight: bold;
}

.pill-blue {
    background-color: #0c8bca;
}

.injection--system .col-12,
.injection--system .col {
    z-index: 2;
}

.injection--system .number-blue-1 {
    z-index: 0;
}

.injection--system .number-blue-2 {
    margin-top: -200px;
    margin-right: 0;
    text-align: right;
    z-index: 0;
}

.injection--system .number-blue-3 {
    margin-left: -50px;
    margin-right: -40px;
    z-index: 0;
}

.injection--system .float {
    float: right;
    max-width: 400px;
}

@media screen and (max-width: 1024px) {
    .injection--system {
        display: flex;
        flex-direction: column;
        gap: 40px;
    }

    .injection--system .float {
        float: none;
        max-width: 100%;
        order: 2;
    }

    .injection--system>.row:nth-child(3) {
        order: 3;
    }

    .injection--system .number-blue-2 {
        margin-top: -100px;
        text-align: left;
    }

    .injection--system .number-blue-3 {
        margin-left: 0;
        margin-right: 0;
    }
}

.double {
    font-size: 2rem;
}

.bigger {
    font-size: 1.5rem;
}

@media screen and (max-width: 768px) {
    .double {
        font-size: 1.5rem;
    }

    .bigger {
        font-size: 1.2rem;
    }
}

.text-blue {
    color: #6588C6;
}

.small,
small {
    font-size: 80%;
}

.img-area-a,
.img-area-b,
.img-area-c {
    position: relative;
}

.img-area-b img {
    position: absolute;
    bottom: 0;
    width: 95%;
    right: 0px;
}

.img-area-c img {
    position: absolute;
    bottom: 0;
    width: 80%;
    right: 0px;
}

.img-area-a img {
    position: absolute;
    bottom: 0;
    width: 90%;
    left: 0;
}

.text-image {
    max-width: 180px;
    margin: 0;
    width: 80%;
}

img.aspect-ratio-5-4 {
    aspect-ratio: 365 / 307;
    object-fit: contain;
}

@media (max-width: 768px) {
    div:has(> .text-image) {
        display: flex;
        justify-content: center;
    }

    img.aspect-ratio-5-4 {
        aspect-ratio: unset;
        object-fit: contain;
    }
}

/*  */

.img-group{
    position: relative;
}
.img-group .icon-absolute{
    position: absolute;
    width: 25%;
    left: 0;
    bottom: 0;
}

@media only screen and (max-width: 768px) {
    .img-group .icon-absolute {
        width: 20%;
        bottom: 15%;
    }
}

/* page-skin-beauty-treatment */
@media only screen and (max-width: 1024px) {
    .page-skin-beauty-treatment h2,
    .page-skin-beauty-treatment .double{
        font-size: 28px;
    }
}
@media only screen and (max-width: 768px) {
    .page-skin-beauty-treatment h2,
    .page-skin-beauty-treatment .double{
        font-size: 18px;
    }

    .page-skin-beauty-treatment .double br {
        display: none;
    }

    .page-skin-beauty-treatment header{
        min-height: 70px;
    }
}
